Basal body timing
نویسندگان
چکیده
منابع مشابه
Basal body timing
ggregation of ␥-tubulin, pericentrin, and myosin II (GPM) precedes de novo basal body assembly, according to a report from Kim et al. on page 719. The number of basal bodies formed is controlled by the duration of ␥-tubulin phosphorylation. Until now, it has not been clear whether basal body and centriole formation occurred before or after clouds of pericentriolar material take shape. To answer...
متن کاملMegaphylogeny, cell body plans, adaptive zones: causes and timing of eukaryote basal radiations.
I discuss eukaryote megaphylogeny and the timing of major innovations in the light of multigene trees and the rarity of marine/freshwater evolutionary transitions. The first eukaryotes were aerobic phagotrophs, probably substratum-associated heterotrophic amoeboflagellates. The primary eukaryote bifurcation generated unikonts (ancestrally probably unicentriolar, with a conical microtubular [MT]...
متن کاملBasal body components exhibit differential protein dynamics during nascent basal body assembly.
Basal bodies organize cilia that are responsible for both mechanical beating and sensation. Nascent basal body assembly follows a series of well characterized morphological events; however, the proteins and their assembly dynamics for new basal body formation and function are not well understood. High-resolution light and electron microscopy studies were performed in Tetrahymena thermophila to ...
متن کاملNew Tetrahymena basal body protein components identify basal body domain structure
Basal bodies organize the nine doublet microtubules found in cilia. Cilia are required for a variety of cellular functions, including motility and sensing stimuli. Understanding this biochemically complex organelle requires an inventory of the molecular components and the contribution each makes to the overall structure. We define a basal body proteome and determine the specific localization of...
متن کاملBasal body docking in airway ciliated cells
Multiciliated cells (MCCs) in the respiratory epithelium play crucial roles in the innate defense system against airborne pathogens and pollutants. Each MCC possesses 200-300 cilia on their apical surface, which beat in a synchronized manner to clear mucus with foreign particles from the respiratory tract. Ciliary dysfunction leads to serious respiratory diseases including chronic infection as ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2005
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1695iti1